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Antibodies

PMEL Rabbit monoclonal antibody

Product Sizes
5 ul
£ POA
A23684-5UL
20 ul
£164.00
A23684-20UL
100 ul
£342.00
A23684-100UL
500 ul
£1532.00
A23684-500UL
1000 ul
£2704.00
A23684-1000UL
About this Product
SKU:
A23684
Additional Names:
D12S53E|gp100|HMB-45|HMB45|ME20|ME20-M|ME20M|P1|P100|PMEL|PMEL17|SI|SIL|SILV
Application:
ELISA, IHC-Paraffin, Western Blot
Clonality:
Monoclonal
Extra Details:
This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants.
Formulation:
Unmodified
Host:
Rabbit
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Isotype:
IgG
Molecular Weight:
100kDa
Purification:
Affinity Purified
Reactivities:
Human
Sequence:
KVPRNQDWLGVSRQLRTKAWNRQLYPEWTEAQRLDCWRGGQVSLKVSNDGPTLIGANASFSIALNFPGSQKVLPDGQVIWVNNTIINGSQVWGGQPVYPQETDDACIFPDGGPCPSGSWSQKRSFVYVWKTWGQYWQVLGGPVSGLSIGTGRAMLGTHTMEVTVYHRRGSRSYVPLAHSSSAFTITD
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
ABclonal Technology
Type:
Antibody: Monoclonal Antibody
  • Manufacturer's Data Sheet:A23684
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