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Antibodies

pan 14-3-3 Rabbit polyclonal antibody

Product Sizes
20 ul
£152.00
A23674-20UL
100 ul
£336.00
A23674-100UL
500 ul
£1258.00
A23674-500UL
1000 ul
£2228.00
A23674-1000UL
About this Product
SKU:
A23674
Additional Names:
14-3-3|HS1|pan 14-3-3|S1C5|YWHA
Application:
ELISA, Western Blot
Clonality:
Polyclonal
Extra Details:
This gene encodes a cell cycle checkpoint protein. The encoded protein binds to translation and initiation factors and functions as a regulator of mitotic translation. In response to DNA damage this protein plays a role in preventing DNA errors during mitosis.This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.
Formulation:
Unmodified
Host:
Rabbit
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Isotype:
IgG
Molecular Weight:
27-29kDa
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Non-human Primate, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
ABclonal Technology
Type:
Antibody: Polyclonal Antibody
  • Manufacturer's Data Sheet:A23674