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Antibodies

MAP3K8 Rabbit polyclonal antibody

Product Sizes
20 ul
£152.00
A15623-20UL
100 ul
£336.00
A15623-100UL
500 ul
£1258.00
A15623-500UL
1000 ul
£2228.00
A15623-1000UL
About this Product
SKU:
A15623
Additional Names:
AURA2|c-COT|COT|EST|ESTF|MAP3K8|MEKK8|Tpl-2|TPL2
Application:
ELISA, Western Blot
Clonality:
Polyclonal
Extra Details:
This gene is an oncogene that encodes a member of the serine/threonine protein kinase family. The encoded protein localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways. This protein was shown to activate IkappaB kinases, and thus induce the nuclear production of NF-kappaB. This protein was also found to promote the production of TNF-alpha and IL-2 during T lymphocyte activation. This gene may also utilize a downstream in-frame translation start codon, and thus produce an isoform containing a shorter N-terminus. The shorter isoform has been shown to display weaker transforming activity. Alternate splicing results in multiple transcript variants that encode the same protein.
Host:
Rabbit
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Isotype:
IgG
Molecular Weight:
52kDa
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Sequence:
MEYMSTGSDNKEEIDLLIKHLNVSDVIDIMENLYASEEPAVYEPSLMTMCQDSNQNDERSKSLLLSGQEVPWLSSVRYGTVEDLLAFANHISNTAKHFYG
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
ABclonal Technology
Type:
Antibody: Polyclonal Antibody
  • Manufacturer's Data Sheet:A15623