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Antibodies

IL6ST Rabbit polyclonal antibody

Product Sizes
20 ul
£152.00
A14656-20UL
100 ug
£336.00
A14656-100UG
500 ul
£1258.00
A14656-500UL
1000 ul
£2228.00
A14656-1000UL
About this Product
SKU:
A14656
Additional Names:
CD130|CDW130|GP130|HIES4|HIES4A|HIES4B|IL-6RB|IL6ST|IMD94|sGP130|STWS2
Application:
ELISA, IHC-Paraffin, Western Blot
Clonality:
Polyclonal
Extra Details:
The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17.
Formulation:
Unmodified
Host:
Rabbit
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Isotype:
IgG
Molecular Weight:
130kDa
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Sequence:
PSISSSDENESSQNTSSTVQYSTVVHSGYRHQVPSVQVFSRSESTQPLLDSEERPEDLQLVDHVDGGDGILPRQQYFKQNCSQHESSPDISHFERSKQVSSVNEEDFVRLKQQISDHISQSCGSGQMKMFQEVSAADAFGPGTEGQVERFETVGMEAATDEGMPKSYLPQTVRQGGYMPQ
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
ABclonal Technology
Type:
Antibody: Polyclonal Antibody
  • Manufacturer's Data Sheet:A14656