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Antibodies

TNFRSF13C Rabbit polyclonal antibody

Product Sizes
20 ul
£152.00
A14299-20UL
100 ul
£336.00
A14299-100UL
500 ul
£1258.00
A14299-500UL
1000 ul
£2228.00
A14299-1000UL
About this Product
SKU:
A14299
Additional Names:
BAFF-R|BAFFR|BROMIX|CD268|CVID4|prolixin|TNFRSF13C
Application:
ELISA, Western Blot
Clonality:
Polyclonal
Extra Details:
B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.
Formulation:
Unmodified
Host:
Rabbit
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Isotype:
IgG
Molecular Weight:
38kda
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Sequence:
MRRGPRSLRGRDAPAPTPCVPAECFDLLVRHCVACGLLRTPRPKPAGASSPAPRTALQPQESVGAGAGEAALPLPGLLFG
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
ABclonal Technology
Type:
Antibody: Polyclonal Antibody
  • Manufacturer's Data Sheet:A14299