Anti-CD47 [A4]

Product Sizes

500 ug

AB01061-34-11-BT-500UG

About this Product

SKU:: AB01061-34-11-BT
Additional Names:: IAP; CD47 antigen; CD47 glycoprotein; Integrin-associated protein; Leukocyte surface antigen CD47; MER6; OA3; Rh-related antigen
Application:: Block/Inhibit/Neutralise, Cell-based/Functional Assay, Flow Cytometry
Buffer:: PBS
translate.label.attr.clone:: A4
Clonality:: Recombinant Monoclonal
Formulation:: PBS only.
Host:: Camelid
Immunogen:: This mouse CD47-specific antagonist nanobody was raised by immunising alpacas with the extracellular Ig-like V-type domain (ECD) of mouse CD47. Subsequently, peripheral blood lymphocytes (PBLs) were isolated from immunized alpacas, and the extracted RNA was used to construct a VHH phage display library. The antibody was generated by panning against the mouse CD47 ECD.
Purification:: Purified
Reactivities:: Mouse
Shipping Conditions:: Blue Ice
Specificity:: This nanobody is specific for murine CD47, a glycosylated five transmembrane protein with a small cytoplasmic domain. CD47 is involved in adhesion through interactions with SIRP (signal regulator protein) and is non-covalently associated with B Beta3 integrins
Storage Conditions:: 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
Supplier:: Absolute Antibody
Type:: Antibody: Recombinant Antibodies

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