Anti-CD47 [A4]
Product Sizes
200 ug
AB01061-23-159-200UG
About this Product
- SKU:
- AB01061-23-159
- Additional Names:
- IAP; CD47 antigen; CD47 glycoprotein; Integrin-associated protein; Leukocyte surface antigen CD47; MER6; OA3; Rh-related antigen
- Application:
- Block/Inhibit/Neutralise, Cell-based/Functional Assay, Flow Cytometry
- Buffer:
- PBS with 0.02% Proclin 300.
- translate.label.attr.clone:
- A4
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric rabbit antibody was made using the variable domain sequences of the original Alpaca VHH format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS with 0.02% Proclin 300.
- Host:
- Rabbit
- Immunogen:
- This mouse CD47-specific antagonist nanobody was raised by immunising alpacas with the extracellular Ig-like V-type domain (ECD) of mouse CD47. Subsequently, peripheral blood lymphocytes (PBLs) were isolated from immunized alpacas, and the extracted RNA was used to construct a VHH phage display library. The antibody was generated by panning against the mouse CD47 ECD.
- Isotype:
- IgG
- Purification:
- Purified
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Specificity:
- This nanobody is specific for murine CD47, a glycosylated five transmembrane protein with a small cytoplasmic domain. CD47 is involved in adhesion through interactions with SIRP (signal regulator protein) and is non-covalently associated with B Beta3 integrins
- Storage Conditions:
- 2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab01061-23.159
