Alpha Synuclein Antibody (pSer129), Clone J18: ATTO 390 Product Size(s) 100 ug £682.00 SMC-600D-A390 Add to order Added to order Academic Pricing Please contact us for academic pricing. Contact Us About this Product SKU: SMC-600D-A390 Additional Names: Phosphorylated alpha synuclein antibody, Phospho anti-alpha Synuclein (S129) antibody, Alpha-synuclein (phospho S129) antibody, alpha Synuclein (phospho Ser129) antibody, alpha-Synuclein Phospho Ser129 Antibody, phospho-A Alpha-Synuclein (Ser129) Antibody, Alpha synuclein antibody, Alpha synuclein antibody phospho Serine 129, Alpha synuclein antibody phospho Ser 129, Alpha synuclein antibody pSerine 129, Alpha synuclein antibody pSer 129, Alpha synuclein antibody phosphoSer 129, Alpha-synuclein antibody, Alpha-synuclein, isoform NACP140 antibody, alphaSYN antibody, NACP antibody, Non A beta component of AD amyloid antibody, Non A4 component of amyloid antibody, Non A4 component of amyloid precursor antibody, Non-A beta component of AD amyloid antibody, Non-A-beta component of alzheimers disease amyloid , precursor of antibody, Non-A4 component of amyloid precursor antibody, Non-A4 component of amyloid, precursor of antibody, PARK 1 antibody, PARK 4 antibody, PARK1 antibody, PARK4 antibody, Parkinson disease (autosomal dominant, Lewy body) 4 antibody, Parkinson disease familial 1 antibody, SNCA antibody, alpha (non A4 component of amyloid precursor) antibody, SYN antibody, Synuclein alpha antibody, Synuclein alpha 140 antibody, Synuclein, alpha (non A4 component of amyloid precursor) antibody, SYUA_HUMAN antibody Application: ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot CE/IVD: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. Clone: J18 Clonality: Monoclonal Conjugate: ATTO 390 Concentration: 1 mg/ml Extra Details: Alpha-Synuclein (SNCA) is expressed predominantly in the brain, where it is concentrated in presynaptic nerve terminals (1). Alpha-synuclein is highly expressed in the mitochondria of the olfactory bulb, hippocampus, striatum and thalamus (2). Functionally, it has been shown to significantly interact with tubulin (3), and may serve as a potential microtubule-associated protein. It has also been found to be essential for normal development of the cognitive functions; inactivation may lead to impaired spatial learning and working memory (4). SNCA fibrillar aggregates represent the major non A-beta component of Alzheimers disease amyloid plaque, and a major component of Lewy body inclusions, and Parkinson's disease. Parkinson's disease (PD) is a common neurodegenerative disorder characterized by the progressive accumulation in selected neurons of protein inclusions containing alpha-synuclein and ubiquitin (5, 6). Alpha synuclein phosphorylated at serine 129 constitutes 90% of the alpha synuclein found in Lewy bodies (7, 8). Gene Details: SNCA Host: Rabbit Immunogen: Human alpha synuclein AA 124-134: AYEMP-pS-EEGYQ-Cys Isotype: IgG Protein Details: P37840 Purification: Affinity Purified Reactivities: Human, Mouse Shipping Conditions: Blue Ice Storage Conditions: 2-8[o]C Supplier: StressMarq Biosciences Type: Antibody: Monoclonal Antibody Size: 100 ug Preservative: 0.09% Sodium azide Accession: NP_000336.1 Need Help?