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Antibodies

Alpha Synuclein Antibody, Clone 3C11: FITC

Product Size(s)
100 ug
£499.00
SMC-530D-FITC
Academic Pricing
Please contact us for academic pricing.
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About this Product
SKU:
SMC-530D-FITC
Additional Names:
Alpha Synuclein Antibody, Non-A beta component of AD amyloid Antibody, Non-A4 component of amyloid precursor Antibody, NACP Antibody, SNCA Antibody, PARK1 Antibody, PARK 1 Antibody, alphaSYN Antibody, PARK 4 antibody, PARK4 antibody, Parkinson disease familial 1 antibody, Parkinson disease (autosomal dominant, Lewy body) 4 antibody, SYN antibody
Application:
Dot Blot, ELISA, Immunocytochemistry, Immunofluorescence, Western Blot
CE/IVD:
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Clone:
3C11
Clonality:
Monoclonal
Conjugate:
FITC
Concentration:
1 mg/ml
Extra Details:
Alpha-Synuclein (SNCA) is expressed predominantly in the brain, where it is concentrated in presynaptic nerve terminals (1). Alpha-synuclein is highly expressed in the mitochondria of the olfactory bulb, hippocampus, striatum and thalamus (2). Functionally, it has been shown to significantly interact with tubulin (3), and may serve as a potential microtubule-associated protein. It has also been found to be essential for normal development of the cognitive functions; inactivation may lead to impaired spatial learning and working memory (4). SNCA fibrillar aggregates represent the major non A-beta component of Alzheimers disease amyloid plaque, and a major component of Lewy body inclusions, and Parkinson's disease. Parkinson's disease (PD) is a common neurodegenerative disorder characterized by the progressive accumulation in selected neurons of protein inclusions containing alpha-synuclein and ubiquitin (5, 6).
Gene Details:
SNCA
Host:
Mouse
Immunogen:
Human alpha synuclein monomer
Isotype:
IgG1
Protein Details:
P37840
Purification:
Protein G Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C
Supplier:
StressMarq Biosciences
Type:
Antibody: Monoclonal Antibody
Size:
100 ug
Preservative:
0.09% Sodium azide
Accession:
NP_000336.1