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Antibodies

LRP4 Antibody, Clone N207/27: FITC

Product Sizes
100 ug
SMC-418D-FITC-100UG
About this Product
SKU:
SMC-418D-FITC
Additional Names:
Corin Antibody, KIAA0816 Antibody, LDLR Antibody, LDLR dan Antibody, Low density lipoprotein receptor related protein 4 Antibody, LRP-4 Antibody, LRP10 Antibody, MEGF7 Antibody, Multiple epidermal growth factor like domains 7 Antibody
Application:
Immunocytochemistry, Immunofluorescence, Western Blot
Buffer:
PBS
CE/IVD:
RUO
translate.label.attr.clone:
N207/27 (Formerly sold as S207-27)
Clonality:
Monoclonal
Conjugate:
FITC
Concentration:
1 mg/ml
Extra Details:
Potential cell surface endocytic receptor, which binds and internalizes extracellular ligands for degradation by lysosomes. It is involved in the negative regulation of the canonical Wnt signaling pathway, being able to antagonize the LRP6-mediated activation of this pathway.
Host:
Mouse
Immunogen:
Fusion protein amino acids 26- 350 (extracellular N-terminus) of mouse LTP4
Isotype:
IgG2a
Purification:
Protein G Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Specificity:
Detects the extracellular domain of LRP4 ~215kDa. Degradation product can be seen at ~150kDa.
Storage Conditions:
See Manual
Supplier:
StressMarq Biosciences
Type:
Antibody: Monoclonal Antibody
Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-LRP4 (Extracellular) Monoclonal Antibody, Clone N207/27 (SMC-418). Tissue: Neuroblastoma cells (SH-SY5Y). Species: Human. Fixation: 4% PFA for 15 min. Primary Antibody: Mouse Anti-LRP4 (Extracellular) Monoclonal Antibody (SMC-418) at 1:200 for overnight at 4°C with slow rocking. Secondary Antibody: AlexaFluor 488 at 1:1000 for 1 hour at RT. Counterstain: Phalloidin-iFluor 647 (red) F-Actin stain; Hoechst (blue) nuclear stain at 1:800, 1.6mM for 20 min at RT. (A) Hoechst (blue) nuclear stain. (B) Phalloidin-iFluor 647 (red) F-Actin stain. (C) LRP4 (Extracellular) Antibody (D) Composite.
Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-LRP4 Monoclonal Antibody, Clone N207/27 (SMC-418). Tissue: COS cells transfected with 2 ug human LRP4 plasmid. Species: Human. Fixation: 4% PFA for 10 min. Primary Antibody: Mouse Anti-LRP4 Monoclonal Antibody (SMC-418) at 1:100 for 1 hour at RT. Secondary Antibody: Goat anti-mouse: Alexa 488. Counterstain: DAPI.
Western Blot analysis of Rat brain membrane lysate showing detection of LRP4 protein using Mouse Anti-LRP4 Monoclonal Antibody, Clone N207/27 (SMC-418). Primary Antibody: Mouse Anti-LRP4 Monoclonal Antibody (SMC-418) at 1:500, 1:1000, and 1:2000.