LRP4 (Extracellular) Antibody, Clone N207/27: FITC
Product Sizes
100 ug
SMC-418D-FITC-100UG
About this Product
- SKU:
- SMC-418D-FITC
- Additional Names:
- LRP4, LRP-4, LRP10, MEGF7, Low density lipoprotein receptor related protein 4, Multiple epidermal growth factor like domains 7, LDLR dan, LDLR, KIAA0816, Corin
- Application:
- Immunocytochemistry, Immunofluorescence, Western Blot
- Buffer:
- 640.91mM DMSO, 136.36 mM Ethanolamine, 126.89 mM chlorides, 9.09mM phosphates, 9.09mM NaHCO3
- CE/IVD:
- RUO
- translate.label.attr.clone:
- N207/27 (Formerly sold as S207-27)
- Clonality:
- Monoclonal
- Conjugate:
- FITC
- Concentration:
- 1 mg/ml
- Extra Details:
- LRP4 (Low-Density Lipoprotein Receptor-Related Protein 4) is a transmembrane receptor essential for neuromuscular junction formation and synaptic signaling. It acts as a co-receptor for agrin and MuSK, facilitating synapse development and maintenance. In the central nervous system, LRP4 influences astrocyte-neuron communication and synaptic plasticity. Mutations or autoantibodies targeting LRP4 are linked to myasthenia gravis and may contribute to cognitive dysfunction. Emerging evidence suggests LRP4 plays a role in neurodegenerative diseases by modulating synaptic integrity and glial function. Its involvement in both peripheral and central synaptic regulation positions LRP4 as a promising target for therapeutic intervention in neuromuscular and neurodegenerative disorders.
- Host:
- Mouse
- Immunogen:
- Fusion protein amino acids 26- 350 (extracellular N-terminus) of mouse LTP4
- Isotype:
- IgG2a
- Purification:
- Protein G Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Specificity:
- Detects the extracellular domain of LRP4 ~215kDa. Degradation product can be seen at ~150kDa.
- Storage Conditions:
- See Manual
- Supplier:
- StressMarq Biosciences
- Type:
- Antibody: Monoclonal Antibody
