(NLysNLeuNspe)3-NH2
About this Product
- SKU:
- PT-010
- Additional Names:
- (NLysNLeuNspe)3-NH2, NLys-NLeu-Nspe-NLy-sNLeu-Nspe-NLys-NLeu-Nspe-NH2, Peptoids, poly-N-substituted glycines, antibacterial, antiparasitic
- Extra Details:
- Peptoids are peptide-mimicking poly-N-substituted glycines, which exhibit enhanced physiological stability and are known to have antibacterial and antiparasitic qualities. They have recently been shown to have activity against Leishmania mexicana axenic amastigotes.
- Immunogen:
- Antibacterials
- Molecular Weight:
- 1224.6
- Physical State:
- Freeze dried solid
- Purity:
- >90%
- References:
- <p>Chongsiriwatana et al (2008) Peptoids that mimic the structure, function, and mechanism of helical antimicrobial peptides. Proc. Natl. Acad. Sci <strong>105</strong>(8) 2794 DOI: 10.1073/pnas.0708254105 </p><p>Zuckermann (2011) Peptoid origins. Biopolymers, <strong>96</strong> 545 doi:10.1002/bip.21573 </p><p>Sun and Zuckermann (2013) Peptoid Polymers: A Highly Designable Bioinspired Material. ACS Nano<strong> 7</strong>(6) 4715 https://doi.org/10.1021/nn4015714 </p><p>Huang et al (2014) Learning from Host-Defense Peptides: Cationic, Amphipathic Peptoids with Potent Anticancer Activity. PLoS ONE <strong>9</strong>(2) e90397. https://doi.org/10.1371/journal.pone.0090397 </p><p>Eggimann et al (2015) Investigating the Anti-leishmanial Effects of Linear Peptoids. ChemMedChem. <strong>10</strong> 233 doi:10.1002/cmdc.201402416</p>
- Sequence:
- NLys-NLeu-Nspe-NLy-sNLeu-Nspe-NLys-NLeu-Nspe-NH2
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store desiccated, frozen and in the dark
- Size:
- 1 mg
- Supplier:
- Isca Biochemicals
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Solubility:
- Soluble in dilute acid
- Formula:
- C66 H105 N13 O9