alpha-MSH
About this Product
- SKU:
- MC-010
- Additional Names:
- a-Melanotropin, a-N-acetyl-ACTH(1-13)-NH2, alpha-melanocyte-stimulating hormone|A Alpha-MSH, a-Melanotropin, a-N-acetyl-ACTH(1-13)-NH2, SYSMEHFRWGKPV, 581-05-5, MC-010
- CAS Number:
- 581-05-5
- Extra Details:
- alpha-MSH is an endogenous melanocortin receptor agonist with Ki values of 0.12, 31, 660 and 5700 nM for MC1, MC3, MC4 and MC5 receptors respectively. alpha-MSH is primarily a pigmentary hormone of the vertebrates and reduces the concentration of proinflammatory mediators through the induction of cyclic adenosine monophosphate (cAMP), controlling inflammation in the brain and peripheral organs. alpha-MSH also possesses antimicrobial properties.
- Immunogen:
- Antibacterials,Melanocortin receptors
- Molecular Weight:
- 1664.88
- Physical State:
- Freeze dried solid
- Purity:
- >95%
- References:
- <p>D'Agostino and Diano (2010) Alpha-melanocyte stimulating hormone: production and degradation. J Mol Med (Berl). <strong>88</strong>(12) 1195 doi:10.1007/s00109-010-0651-0</p><p>Singh and Mukhopadhyay (2014) Alpha-Melanocyte Stimulating Hormone: An Emerging Anti-Inflammatory Antimicrobial Peptide BioMed Research International Article ID 874610 https://doi.org/10.1155/2014/874610</p><p>Kravchychyn et al (2018) The Long-Term Impact of High Levels of Alpha-Melanocyte-Stimulating Hormone in Energy Balance Among Obese Adolescents. Ann Nutr Metab. <strong>72</strong> 279 doi: 10.1159/000488005<br></p>
- Sequence:
- AcSer-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store dry, frozen and in the dark
- Size:
- 5 mg
- Supplier:
- Isca Biochemicals
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Solubility:
- Soluble to 0.60 mg/ml in water
- Formula:
- C77H109N21O19S