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Antibodies

Human CD3 Antibody : FITC

Product Sizes
100 tests
OASB00983-100TESTS
About this Product
SKU:
OASB00983
Additional Names:
T-cell surface glycoprotein CD3 epsilon chain|T3E, TCRE, IMD18
Application:
Flow Cytometry, IHC-Frozen, IHC-Paraffin, Immunocytochemistry, Western Blot
translate.label.attr.clone:
UCHT1
Clonality:
Monoclonal
Conjugate:
FITC
Extra Details:
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.
Host:
Mouse
Immunogen:
Human peripheral blood lymphocytes from a patient with Sezary's syndrome and infant thymocytes
Isotype:
IgG1
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
CD3
Storage Conditions:
2-8[o]C
Supplier:
Aviva Systems Biology
Type:
Antibody: Monoclonal Antibody