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Antibodies

anti-RIPK1 / RIP1 phospho (Ser166) antibody [YJY-1-5]

Product Sizes
100 ul
£593.00
ARG66476-100UL
Academic Pricing
Please contact us for academic pricing.
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About this Product
SKU:
ARG66476
Additional Names:
Receptor-interacting protein 1; RIP-1; Receptor-interacting serine/threonine-protein kinase 1; RIP; Cell death protein RIP; RIP1; EC 2.7.11.1; Serine/threonine-protein kinase RIP
Application:
IHC-Frozen, IHC-Paraffin, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Buffer:
PBS, 0.01% Sodium azide, 40% Glycerol and BSA.
CE/IVD:
RUO
Clone:
YJY-1-5
Clonality:
Monoclonal
Extra Details:
RIPK1 / RIP1 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein plays a role in inflammation and cell death in response to tissue damage, pathogen recognition, and as part of developmental regulation. RIPK1/RIPK3 kinase-mediated necrosis is referred to as necroptosis. Genetic disruption of this gene in mice results in death shortly after birth. [provided by RefSeq, Aug 2017]
Host:
Rabbit
Isotype:
IgG
Purification:
Protein A Purified; Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C
Supplier:
Arigo Biolaboratories
Type:
Antibody: Monoclonal Antibody
Immunohistochemistry: Paraffin-embedded rat lung tissue from rat silicosis model. Antigen Retrieval: Citrate buffer (pH 6.0) at high pressure and temperature. The tissue section was stained with ARG66476 anti-RIPK1 / RIP1 phospho (Ser166) antibody [YJY-1-5] at 1:70 dilution. The picture on the right is negative control.
Western blot: MLE cells untreated control (C) or treated with 20 ng/ml of TNF alpha, 1 uM of BV-6 and 20 uM of Z-VAD-FMK for 8 hours (T). Cell lysates were stained with ARG66476 anti-RIPK1 / RIP1 phospho (Ser166) antibody [YJY-1-5].