Human VEGF-D Protein, His Tag Citation Available Product Size(s) 100 ug £382.00 VED-H5228-100UG Add to order Added to order 1 mg £2265.00 VED-H5228-1MG Add to order Added to order Academic Pricing Please contact us for academic pricing. Contact Us About this Product SKU: VED-H5228 Additional Names: FIGF|VEGFD Buffer: PBS, pH7.4 Extra Details: Vascular endothelial growth factor D (VEGF-D) is also known as C-fos induced growth factor (FIGF), which belongs to the PDGF / VEGF growth factor family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. This secreted protein VEGF-D / FIGF undergoes a complex proteolytic maturation, generating multiple processed forms that bind and activate VEGFR-2 and VEGFR-3. The structure and function of this protein is similar to those of VEGFC. FIGF / VEGF-D is highly expressed in lung, heart, small intestine and fetal lung. FIGF / VEGF-D may function in the formation of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR / FLK1) and VEGFR-3 (FLT4) receptors. Molecular Weight: 13.4 kDa Physical State: Powder Shipping Conditions: Ambient Storage Conditions: -20[o]C Supplier: ACRO Biosystems Type: Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins Epitope Tag: 9xHIS Tag Long Description: Vascular endothelial growth factor D (VEGF-D) is also known as C-fos induced growth factor (FIGF), which belongs to the PDGF / VEGF growth factor family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. This secreted protein VEGF-D / FIGF undergoes a complex proteolytic maturation, generating multiple processed forms that bind and activate VEGFR-2 and VEGFR-3. The structure and function of this protein is similar to those of VEGFC. FIGF / VEGF-D is highly expressed in lung, heart, small intestine and fetal lung. FIGF / VEGF-D may function in the formation of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR / FLK1) and VEGFR-3 (FLT4) receptors. Accession: AAH27948 Human VEGF-D, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. Immobilized Human VEGF R3, Fc Tag (Cat. No. FL4-H5251) at 5 ug/mL (100 uL/well) can bind Human VEGF-D, His Tag (Cat. No. VED-H5228) with a linear range of 0.08-0.6 ug/mL (QC tested). Need Help? View product citations for antibody VED-H5228 on CiteAb