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Biotinylated Human PD-L2 / B7-DC Protein, Fc,Avitag[TM] (MALS verified)

Product Size(s)
25 ug
£382.00
PD2-H82F6-25UG
200 ug
£1582.00
PD2-H82F6-200UG
Academic Pricing
Please contact us for academic pricing.
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About this Product
SKU:
PD2-H82F6
Additional Names:
Butyrophilin B7-DC|CD273|PDCD1 ligand 2|PDCD1L2|PDCD1LG2|PDL2|PD-L2
Buffer:
Tris with Glycine, Arginine and NaCl, pH7.5
Conjugate:
Biotin
Extra Details:
Programmed cell death 1 ligand 2 (PD-L2 or PDCD1 ligand 2) is also known as Butyrophilin B7-DC, CD antigen CD273, which belongs to the immunoglobulin superfamily or BTN/MOG family. The expression of PD-L2 is up-regulated by IFNG/IFN-gamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL-4. PD-L2 Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PD-L2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
Molecular Weight:
51.0 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
Epitope Tag:
AviTag™, Fc Tag
Long Description:
Programmed cell death 1 ligand 2 (PD-L2 or PDCD1 ligand 2) is also known as Butyrophilin B7-DC, CD antigen CD273, which belongs to the immunoglobulin superfamily or BTN/MOG family. The expression of PD-L2 is up-regulated by IFNG/IFN-gamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL-4. PD-L2 Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PD-L2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
Accession:
AAI13679
Biotinylated Human PD-L2, Fc,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Human PD-1, Fc Tag (Cat. No. PD1-H5257) at 2 ug/mL (100 uL/well) can bind Biotinylated Human PD-L2, Fc,Avitag (Cat. No. PD2-H82F6) with a linear range of 0.5-16 ng/mL (QC tested).