Biotinylated Human PD-L2 / B7-DC Protein, Fc,Avitag[TM] (MALS verified) Citation Available Product Size(s) 25 ug £382.00 PD2-H82F6-25UG Add to order Added to order 200 ug £1582.00 PD2-H82F6-200UG Add to order Added to order Academic Pricing Please contact us for academic pricing. Contact Us About this Product SKU: PD2-H82F6 Additional Names: Butyrophilin B7-DC|CD273|PDCD1 ligand 2|PDCD1L2|PDCD1LG2|PDL2|PD-L2 Buffer: Tris with Glycine, Arginine and NaCl, pH7.5 Conjugate: Biotin Extra Details: Programmed cell death 1 ligand 2 (PD-L2 or PDCD1 ligand 2) is also known as Butyrophilin B7-DC, CD antigen CD273, which belongs to the immunoglobulin superfamily or BTN/MOG family. The expression of PD-L2 is up-regulated by IFNG/IFN-gamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL-4. PD-L2 Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PD-L2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. Molecular Weight: 51.0 kDa Physical State: Powder Shipping Conditions: Ambient Storage Conditions: -20[o]C Supplier: ACRO Biosystems Type: Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein Epitope Tag: AviTag™, Fc Tag Long Description: Programmed cell death 1 ligand 2 (PD-L2 or PDCD1 ligand 2) is also known as Butyrophilin B7-DC, CD antigen CD273, which belongs to the immunoglobulin superfamily or BTN/MOG family. The expression of PD-L2 is up-regulated by IFNG/IFN-gamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL-4. PD-L2 Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PD-L2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. Accession: AAI13679 Biotinylated Human PD-L2, Fc,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. Immobilized Human PD-1, Fc Tag (Cat. No. PD1-H5257) at 2 ug/mL (100 uL/well) can bind Biotinylated Human PD-L2, Fc,Avitag (Cat. No. PD2-H82F6) with a linear range of 0.5-16 ng/mL (QC tested). Need Help? View product citations for antibodies PD2-H82F6 on CiteAb