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Antibodies

CD40 Ligand

Product Sizes
100 ug
£674.12
103-M142-100UG
About this Product
SKU:
103-M142
Additional Names:
Cd40lg; IGM; IMD3; Ly62; TRAP; gp39; CD154; Cd40l; HIGM1; Ly-62; T-BAM; CD40-L; Tnfsf5
Application:
Flow Cytometry, Immunohistochemistry
Buffer:
PBS
translate.label.attr.clone:
MAB0712
Clonality:
Monoclonal
Extra Details:
CD40 ligand (CD40L), also known as CD154, TNFSF5, TRAP or gp39, is a 260 amino acid type II transmembrane glycoprotein belonging to the TNF family. Murine CD40L consists of a 22 aa cytoplasmic domain, a 24 aa transmembrane domain, and 214 aa extracellular domain bearing a single glycosylation site. CD40L is expressed predominantly on activated CD4+ T lymphocytes, and also found in other types of cells, including NK cells, mast cells, basophils and eosinophils. Murine CD40L shares 78% amino acid sequence identity with human CD40L. Native bioactive soluble CD40L exists. Soluble human trimeric CD40L secreted by stimulated T cells has been shown to be generated by proteolysis in the microsomes. Both membrane bound and soluble CD40L induce similar effects on B cells.
Formulation:
lyophilized
Host:
Hamster
Immunogen:
Mouse Th1 cells
Isotype:
IgG2
Purification:
Protein G/A chromatography
Reactivities:
Mouse
Shipping Conditions:
Ambient
Storage Conditions:
-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
ReliaTech
Type:
Antibody: Monoclonal Antibody