Skip to content

Basket

You currently have no items in your basket.

Total (excl. vat) £0.00
View basket & checkout
Antibodies

FAS

Product Sizes
100 ug
£674.12
101-M134-100UG
About this Product
SKU:
101-M134
Additional Names:
FAS; APT1; CD95; FAS1; APO-1; FASTM; ALPS1A; TNFRSF6
Application:
IHC-Paraffin, Western Blot
Buffer:
PBS
translate.label.attr.clone:
12J3
Clonality:
Monoclonal
Extra Details:
Fas, also known as APO1, CD95, and TNFRSF6, was originally identified as a cellsurface protein which binds to monoclonal antibodies that were cytolytic for various human cell lines. In the new TNF Receptor superfamily nomenclature, Fas is referred to as TNFRSF6. Human Fas cDNA encodes a 325 amino acid (aa) residue type 1 membrane protein that belongs to the TNF and NGF receptor family. Alternatively spliced cDNAs encoding multiple Fas isoforms, including a soluble form of Fas lacking the transmembrane domain, have also been identified. Fas is highly expressed in epithelial cells, hepatocytes, activated mature lymphocytes, virus-transformed lymphocytes, and other tumor cells. Fas expression has also been detected in mouse thymus, liver, heart, lung, kidney and ovary. The ligand for Fas (FasL) has been identified and shown to be a member of the TNF family of type 2 membrane proteins. Fas-L is predominantly expressed by activated Tlymphocytes, NK cells, and in tissues with immuneprivileged sites. Soluble Fas-L can be produced by proteolysis of membrane-associated Fas.
Formulation:
lyophilized
Host:
Mouse
Immunogen:
recombinant human FAS
Isotype:
IgG1
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Ambient
Storage Conditions:
-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
ReliaTech
Type:
Antibody: Monoclonal Antibody