anti-Perilipin 2 N-terminus, guinea pig polyclonal antibody
Product Sizes
100 ul
£384.00
GP40-100UL
About this Product
- SKU:
- GP40
- Additional Names:
- Perilipin-2, Adipophilin, Adipose differentiation-related protein, ADRP, PLIN2, ADFP
- Application:
- Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
- CE/IVD:
- RUO
- Clonality:
- Polyclonal
- Extra Details:
- Perilipin 2/Adipophilin/ADRP/PLIN2 (a member of the PLIN/PAT family) is a ubiquitous component of lipid droplets. It has been found in milk fat globule membranes and on the surface of lipid droplets in various cultured cell lines; inducible by etomoxir. Enhanced expression of Perilipin 2/Adipophilin/ADRP/PLIN2 is a useful marker for pathologies characterized by increased lipid droplet accumulation. Such diseases include atheroma, steatosis, obesity and certain cases of liposarcoma. It also seems to be a potent marker for atherosclerosis. ADRP can also be used to study the virus entry via lipid droplets. Polypeptide reacting: specific for Perilipin 2/Adipophilin/ADRP/PLIN2, MW 48,100 (calculated from aa sequence data); apparent Mr 52,000 (after SDS-PAGE); pI 6.72. Immunolocalization: Adipophilin/PLIN2 is positively detected in the glandular cells of lactating mammary gland (ductal cells are negative), zona fasciculata of the adrenal gland, Sertoli cells of the testis, and in fat-accumulating hepatocytes of alcoholic cirrhotic fatty liver; adipocytes are negative. Also positively stained are lipid-storing CD 68-positive macrophages.
- Formulation:
- Contains 0.09% sodium azide
- Host:
- Guinea Pig
- Immunogen:
- Synthetic peptide (N-terminal aa 1-29 of human and murine adipophilin)
- Purification:
- Stabilized antiserum
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Progen
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:GP40-1
