Anti-Hu CD129 PE
Product Sizes
100 tests
AFC-F7XLZI-100TESTS
About this Product
- SKU:
- AFC-F7XLZI
- Additional Names:
- IL9R
- Application:
- Flow Cytometry
- Buffer:
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- translate.label.attr.clone:
- AH9R7
- Clonality:
- monoclonal
- Conjugate:
- PE
- Extra Details:
- CD129 serves as the high affinity alpha subunit of IL-9 receptor. It associates with CD132, the common gamma chain shared by receptors of many different cytokines. CD129 is expressed at low levels by T and B cells, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons. Its signaling (through JAK/STAT pathways) results in proliferative and anti-apoptotic response, which is critical e.g. for intrathymic T cell development and survival of various cell types. The gene for CD129 is located at the pseudoautosomal regions of X and Y chromosomes and it may be related with the development of asthma.
- Format:
- PE
- Immunogen:
- Human CD129-transfected cell line
- Isotype:
- IgG2b k
- Purification:
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- Research Area:
- Cell Signaling
- Shipping Conditions:
- Blue Ice
- Specificity:
- The mouse monoclonal antibody AH9R7 recognizes an extracellular epitope of CD129 / IL-9R alpha, a 57 kDa type I transmembrane glycoprotein expressed at low levels by lymphocytes, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons.
- Storage Conditions:
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
- Manufacturer's Data Sheet:Anti-Hu CD129 PE
