Albumin, Rat
Product Sizes
25 mg
16-16-011202-RAT-25MG
About this Product
- SKU:
- 16-16-011202-RAT
- Additional Names:
- Alb|Cell Culture Media, In Vitro Diagnostic, Calibrators, Control, Antisera Production, Protein Chemistry, Therapeutics Research
- Application:
- Control, Tissue Culture
- Buffer:
- Salt-free lyophilized solid
- CAS Number:
- 70024-90-7
- CE/IVD:
- RUO
- Extra Details:
- Albumin constitutes 60% of plasma proteins and exhibits exceptional structural stability due to its 17 disulfide bonds and conserved N-glycosylation. Beyond maintaining 80% of plasma oncotic pressure to prevent vascular fluid leakage, albumin binds and transports hydrophobic ligands-including fatty acids, steroids, thyroid hormones, calcium ions, and over 90% of circulating drugs-via its dynamic binding pockets. Its free Cys34 residue confers antioxidant properties by scavenging reactive oxygen species. Hypoalbuminemia (<3.5 g/dL) arises from hepatic dysfunction (cirrhosis, hepatitis), renal protein loss (nephrotic syndrome), chronic inflammation, or malnutrition. Clinically, it manifests as edema, ascites, and impaired drug efficacy due to reduced ligand binding. Conversely, glycated albumin contributes to diabetic complications by promoting vascular endothelial dysfunction3. Therapeutically, human serum albumin (HSA) has been administered since 1941 for hypovolemia and burns, with modern 5% and 25% solutions managing ARDS and cardiopulmonary bypass. With a 19-day circulatory half-life, albumin stabilizes cell culture media.
- Formulation:
- Salt-free lyophilized solid
- Molecular Weight:
- 66,000 Da
- Physical State:
- Lyophilized
- Purification:
- Liquid Chromatography Methods
- Shipping Conditions:
- Blue Ice
- Source:
- Rat plasma was obtained from healthy animals of US origin and under the care of a registered veterinarian.
- Storage Conditions:
- -20[o]C
- Supplier:
- Athens Research & Technology Inc.
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Native
