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Assay Kits & ELISAs

arigoPLEX[R] Human Angiogenic Marker Multiplex ELISA kit (VEGF, FGF basic, HGF, IL6)

Product Sizes
96 wells
ARG83510-96WELLS
About this Product
SKU:
ARG83510
Additional Names:
VEGF: VEGFA, Vascular Endothelial Growth Factor A, VP, VEGF-A, VEGF, Vascular Permeability Factor, Vascular Endothelial Growth Factor A121, Vascular Endothelial Growth Factor A165, Vascular Endothelial Growth Factor, MVCD1FGF basic: FGF-2; Fibroblast growth factor 2; bFGF; FGFB; Heparin-binding growth factor 2; BFGF; HBGF-2; Basic fibroblast growth factorHGF: HPTA; Scatter factor; F-TCF; Hepatocyte growth factor; DFNB39; Hepatopoietin-A; HGFB; SFIL6: B-cell stimulatory factor 2; CDF; HSF; BSF-2; Interferon beta-2; IL-6; IFNB2; CTL differentiation factor; Interleukin-6; HGF; Hybridoma growth factor; BSF2; IFN-beta-2
Application:
ELISA
CE/IVD:
RUO
Conjugate:
HRP
Extra Details:
VEGF: Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (By similarity). [UniProt] FGF basic: Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4 (PubMed:8663044). Also acts as an integrin ligand which is required for FGF2 signaling (PubMed:28302677). Binds to integrin ITGAV:ITGB3 (PubMed:28302677). Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration (PubMed:8663044, PubMed:28302677). Functions as a potent mitogen in vitro (PubMed:3732516, PubMed:3964259). Can induce angiogenesis (PubMed:23469107, PubMed:28302677). [UniProt] HGF: Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. [UniProt] IL6: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation. [UniProt]
Immunogen:
Angiogenic
Physical State:
Cell Culture Supernatant, Plasma, Serum
Reactivities:
Human
Sensitivity:
VEGF: 31.25 pg/mlFGF basic: 15.625 pg/mlHGF: 125 pg/mlIL-6: 15.625 pg/ml
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C, -20[o]C
Supplier:
Arigo Biolaboratories
Type:
Assay Kits: ELISAs
ARG83510 arigoPLEX®Human Angiogenic Marker Multiplex ELISA kit results of a typical standard for Human FGF basic run with optical density reading at 450 nm.
ARG83510 arigoPLEX®Human Angiogenic Marker Multiplex ELISA kit results of a typical standard for Human HGF run with optical density reading at 450 nm.
ARG83510 arigoPLEX®Human Angiogenic Marker Multiplex ELISA kit results of a typical standard for Human IL6 run with optical density reading at 450 nm.
ARG83510 arigoPLEX®Human Angiogenic Marker Multiplex ELISA kit results of a typical standard for Human VEGF run with optical density reading at 450 nm.