anti-Acrosin antibody [ACR-2]
About this Product
- SKU:
- ARG62666
- Additional Names:
- Acrosin; EC 3.4.21.10
- Application:
- Immunocytochemistry, Immunofluorescence, Western Blot
- Buffer:
- PBS (pH 7.4) and 15 mM Sodium azide
- CE/IVD:
- RUO
- translate.label.attr.clone:
- ACR-2
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Acrosin is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids. [provided by RefSeq, Jul 2008]
- Host:
- Mouse
- Immunogen:
- Acid extracts of boar spermatozoa were subjected to hydrophobic chromatography and the pooled fraction with reactivity to N-alpha benzoylarginine-4-nitroanilide was used for immunization.
- Isotype:
- IgG1
- Purity:
- >95%
- Purification:
- Protein A Purified
- Reactivities:
- Porcine
- Shipping Conditions:
- Blue Ice
- Specificity:
- The clone ACR-2 reacts with various forms of porcine acrosin (55, 53, 45 and 35 kDa), a typical serine proteinase with trypsin-like specificity. Acrosin is stored in the acrosome of undamaged spermatozoa.
- Storage Conditions:
- -20[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:ARG62666.html
