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Proteins and Peptides

Human Coagulation Factor III / Tissue Factor Protein, Fc Tag (active enzyme, MALS verified)

Product Sizes
100 ug
TF3-H5253-100UG
500 ug
TF3-H5253-500UG
About this Product
SKU:
TF3-H5253
Additional Names:
CD142|Coagulation Factor III|F3|TF|Tissue Factor
Buffer:
50 mM Tris, 150 mM NaCl, pH7.5
Extra Details:
Full-length tissue factor (TF) is a transmembrane receptor and cofactor for factor (F)VII/FVIIa. In addition to full-length TF, an alternative spliced (as) form of TF can be generated that lacks the transmembrane domain and is released fromcells. In contrast to TF, asTF has low procoagulant activity because it lacks the transmembrane domain. Tissue factor is expressed by cells around blood vessels, such as adventitial fibroblasts, and body surfaces, such as epithelial cells, and plays a critical role in hemostasis. TF also contributes to various forms of thrombosis. Many cancers, particularly adenocarcinomas, express high levels of TF. A high level of tumor TF expression is associated with poor prognosis in many types of cancers, including breast, prostate, colorectal, and pancreatic cancer.
Immunogen:
Coagulation Factor III
Molecular Weight:
51.2 kda
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human Tissue Factor, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Human Tissue Factor, Fc Tag (Cat. No. TF3-H5253) at 1 ug/mL (100 uL/well) can bind Anti-TF Antibody, Human IgG1 with a linear range of 0.2-2 ng/mL (Routinely tested).
Immobilized Human Tissue Factor, Fc Tag (Cat. No. TF3-H5253) at 1 ug/mL (100 uL/well) can bind Tisotumab with a linear range of 0.06-4 ng/mL (Routinely tested).