Anti-CCR2 [AbAb-CCR2]
Product Sizes
200 ug
AB02444-8-4-200UG
About this Product
- SKU:
- AB02444-8-4
- Additional Names:
- CD192; C-C chemokine receptor type 2; C-C CKR-2; CC-CKR-2; CCR-2; Monocyte chemoattractant protein 1 receptor; MCP-1-R; JE/FIC receptor; CMKBR2
- Application:
- Block/Inhibit/Neutralise, Flow Cytometry
- Buffer:
- PBS with 0.02% Proclin 300.
- translate.label.attr.clone:
- AbAb-CCR2
- Clonality:
- Recombinant Monoclonal
- Formulation:
- PBS with 0.02% Proclin 300.
- Host:
- Rat
- Immunogen:
- The original antibody was generated by immunizing rats with CHO cells stably transfected with mouse CCR2.
- Isotype:
- IgG2b
- Purification:
- Purified
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody specifically binds mouse CCR2 and does not cross react with mouse CCR5 or human CCR2 and CCR5. CCR2 is a key functional receptor for CCL2 but can also bind CCL7 and CCL12 chemokines. Its binding with CCL2 on monocytes and macrophages mediates chemotaxis and migration. It regulates the expression of T-cell inflammatory cytokines and T-cell differentiation, promoting the differentiatio
- Storage Conditions:
- 2-8[o]C Aliquot.
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab02444-8.4