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Proteins and Peptides

Bz-Arg-Gly-Phe-Phe-Pro-4MbNA (Cathepsin D Substrate)

Product Sizes
1 mg
ECH-880-42-1MG
About this Product
SKU:
ECH-880-42
Extra Details:
Molecular Weight: 881.42Salt Form: HClPurity: >96%Sequence (3-letter): Bz-Arg-Gly-Phe-Phe-Pro-4MbNASequence (1-letter): Bz-RGFFP-4MbNAStorage: -20 °C or belowBz-Arg-Gly-Phe-Phe-Pro-4MbNA is a fluorogenic substrate for Cathepsin D. Cathepsin D is a lysosomal aspartyl protease whose role is to degrade and activate intracellular proteins including hormones enzyme precursors and growth factors. Over expression in tumors stimulates metastasis and considered a marker of poor prognosis in breast cancer.Activity is quantified by release of free fluorescent 4-Methoxy-B Beta-naphthylamine (4MB BetaNA) which excites at 335-350 nm and emits at 410-440 nm.
Molecular Weight:
881.42
Sequence:
Bz-Arg-Gly-Phe-Phe-Pro-4MbNA
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
Echelon Biosciences
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides