BIM Antibody
Product Sizes
100 ug
600-401-Z70-100UG
About this Product
- SKU:
- 600-401-Z70
- Additional Names:
- BCL2L11|Bim Antibody, BAM, BIM, BOD, Bcl-2-like protein 11, Bcl2-interacting mediator of cell death, Bcl2-L-11, BCL2L11
- Application:
- ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- CE/IVD:
- RUO
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bim or BOD in human, mouse and rat. Bim/BOD interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. Bim/BOD induces apoptosis. The messenger RNA of Bim is ubiquitously expressed in multiple tissues and cell lines.
- Formulation:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Host:
- Rabbit
- Immunogen:
- Anti-Bim antibody was prepared from whole rabbit serum produced by repeated immunizations with a peptide corresponding to amino acids near the internal region of human Bim. The immunogen is located within amino acids 80-130 of BIM.
- Isotype:
- IgG
- Physical State:
- Liquid
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Dry Ice
- Specificity:
- Anti-Bim Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with Bim from other sources has not been determined. Predicted species reactivity based on immunogen sequence: Rat: (100%).
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:https://www.rockland.com/search/?searchString=600-401-Z70
