HSP40 Antibody: ATTO 488
Product Sizes
100 ul
SPC-100D-A488-100UL
About this Product
- SKU:
- SPC-100D-A488
- Additional Names:
- DnaJ (HSP40) homolog subfamily B member 1 Antibody, DNAJ1 Antibody, DNAJB1 Antibody, HDJ1 Antibody, HSPF1 Antibody
- Application:
- Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
- CE/IVD:
- RUO
- Clonality:
- Polyclonal
- Conjugate:
- ATTO 488
- Extra Details:
- DnaJ/HSP40 proteins have been preserved throughout evolution and are important for protein translation, folding, unfolding, translocation, and degradation, primarily by stimulating the ATPase activity of chaperone proteins, HSP70s. Because the ATP hydrolysis is essential for the activity of HSP70s, DnaJ/HSP40 proteins actually determine the activity of HSP70s by stabilizing their interaction with substrate proteins. DnaJ/HSP40 proteins all contain the J domain through which they bind to HSP70s. HSP40, also known as HDJ1 (6), is a basic mammalian 40kDa heat shock protein which is not only homologous to the bacterial heat shock protein (DnaJ), but also yeast DnaJ-related proteins such as SCJ1, Sec63/Npl1, YDJ1 and SIS1 (2-5). HSP 40 is inducible by stress including heat after which is moves from the cytoplasm to the nucleus and nucleoli; an intracellular pattern similar to HSC70/HSP70, the mammalian homologues of the bacterial heat shock protein, DnaK (2).
- Host:
- Rabbit
- Immunogen:
- Recombinant purified full-length human HSP40 (no tags)
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- Detects ~40kDa.
- Storage Conditions:
- See Manual
- Supplier:
- StressMarq Biosciences
- Type:
- Antibody: Polyclonal Antibody
