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Antibodies

ATRIP Phospho S239 Antibody

Product Sizes
100 ul
600-401-W95-100UL
About this Product
SKU:
600-401-W95
Additional Names:
ATM, Rad3-related-interacting protein, ATR-interacting protein|ATRIP
Application:
ELISA, Western Blot
Buffer:
0.01 M HEPES, 0.15 M Sodium Chloride
CE/IVD:
RUO
Clonality:
Polyclonal
Extra Details:
ATRIP, ATR interacting protein, binds to ATR to regulate ATR expression, and is an essential component of the DNA damage checkpoint pathway (Cortez et al, 2001). ATR is recruited to DNA lesions in part through its association with ATRIP, which in turn interacts with the single-stranded DNA binding protein RPA (Ball et al, 2007). DNA replication forks may stall as a result of DNA damage causing phosphorylation of several proteins, including BRCA1 when colocalizing with ATR/ATRIP complex and RPA (Venere et al, 2007). The DNA replication fork stall coincides with BRCA1 directly phosphorylating ATRIP at ser239. ATRIP pS239 Antibody is ideal for researchers interested in cancer research.
Formulation:
0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Host:
Rabbit
Immunogen:
Anti-Phospho-Ser239 ATRIP Antibody was produced from rabbits by repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding Ser239 of human ATRIP conjugated to KLH.
Isotype:
IgG
Physical State:
Liquid
Reactivities:
Mouse
Shipping Conditions:
Blue Ice
Specificity:
Anti-ATRIP pS239 Antibody is directed against human ATRIP protein phosphorylated at S239. The antibody was prepared from monospecific antiserum by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific peptide to remove any unwanted reactivities. Assay by immunoelectrophoresis resulted in a sin
Storage Conditions:
Please refer to datasheet
Supplier:
Rockland Inc
Type:
Antibody: Polyclonal Antibody