CCDC134 Antibody
Product Sizes
100 ug
600-401-AF1-100UG
About this Product
- SKU:
- 600-401-AF1
- Additional Names:
- CCDC134|CCDC134 Antibody, dJ821D11.3, Coiled-coil domain-containing protein 134
- Application:
- ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- CE/IVD:
- RUO
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. One such protein is CCDC134, a recently identified secretory protein that has been found to inhibit the transcriptional activity of the Elk1 protein. Overexpression CCDC134 also inhibited the phosphorylation of Erk and JNK/SAPK but not p38 MAPK, while specific siRNA against CCDC134 activated Elk1 transcriptional activity and the phosphorylation of Erk and JNK/SAPK, suggesting a potential inhibiting role of CCDC134 in MAPK-mediated Elk1 transcription. CCDC134 is widely expressing in normal adult tissues, tumors, and cell lines.
- Formulation:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Host:
- Rabbit
- Immunogen:
- Anti-CCDC134 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid synthetic peptide near the N-terminus of human CCDC134.
- Isotype:
- IgG
- Physical State:
- Liquid
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Dry Ice
- Specificity:
- Anti-CCDC134 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with CCDC134 from other sources has not been determined.
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:https://www.rockland.com/search/?searchString=600-401-AF1
