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Proteins and Peptides

Tau-441 (127-421) protein

Product Sizes
20 ug
009-001-T85S-20UG
About this Product
SKU:
009-001-T85S
Additional Names:
MAPT|Tau-F, (N2R4), Tau-4, MAPT, MSTD, PPND, DDPAC, MAPTL, MTBT1, MTBT2, FTDP-17, FLJ31424, MGC138549, Microtubule-associated protein tau
Application:
Western Blot
Buffer:
See application note.
CE/IVD:
RUO
Concentration:
0.2 ug/ul
Extra Details:
Tau-441 or Tau-F is a member of the Tau family of proteins which function to stabilize the microtubules by binding to them. Tau proteins are subject to phosphorylation and this phenomenon regulates the association of the Tau protein with the microtubules (1). Deposits of Alzheimer's disease AD-associated proteins, such as hyperphosphorylated Tau, as well as other shared misfolded proteins, such as, B Beta-amyloid precursor protein (B BetaAPP), ubiquitin, and various chaperones and protein kinases are thought to play a pathologic role in the cognitive decline and muscular failure. Malfunctioning of Tau proteins is associated with microtubules disintegration and collapsing of the neuronal transport system (2). Tau-441 Protein is ideal for investigators involved in Signaling Proteins, Tau Proteins, Invasion/Metastasis, Neurobiology, and p38 Pathway research.
Immunogen:
MAPT
Physical State:
Liquid
Shipping Conditions:
Dry Ice
Specificity:
Recombinant human tag-free Tau-441 (151-421) was expressed in E. coli cells. The purity was determined to be >80% by densitometry.
Storage Conditions:
-70[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Rockland Inc
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins