IFN lambda-2
Product Sizes
5 ug
£178.82
M10-068-5UG
20 ug
£307.06
M10-068-20UG
About this Product
- SKU:
- M10-068
- Additional Names:
- Il28a; Ifnl2; IL-28A; EG330496
- translate.label.attr.clone:
- Rabbit IgG
- Extra Details:
- Human/mouse IFN-lambda 2 or IL-28A, IL-28B (or IFN-lambda 3), and human IL-29 (IFN-lambda 1) are class II cytokine receptor ligands that are distantly related to members of the IL-10 family (11 - 13% amino acid (aa) sequence identity) and type I IFN family (15 - 19% aa sequence identity). These cytokines exert bioactivities that overlap those of type I IFNs, including antiviral activity and up-regulation of MHC class I antigen expression. The proteins signal through the same heterodimeric receptor complex that is composed of the IL-10 receptor beta (IL-10 R beta) and a novel IL-28 receptor alpha (IL-28 R alpha, also known as IFN-lambda R1). Mouse IL-28 shares 61%, 62%, and 52% aa identity with human IL-28A, IL-28B, and IL-29, respectively.
- Formulation:
- lyophilized
- Host:
- Rabbit
- Molecular Weight:
- 19.8 kDa
- Purity:
- > 98% by SDS-PAGE & HPLC analyses
- Reactivities:
- Human, Mouse, Virus
- Sequence:
- MDPVPRATRL PVEAKDCHIA QFKSLSPKEL QAFKKA KDAI EKRLLEKDMR CSSHLISRAW DLKQLQVQER PKALQAEVAL TLKVWENMTD SALATILGQP LHTLSHIHSQ LQTCTQLQAT AEPKPPSRRL SRWLHRLQEA QSKETPGCLE DSVTSNLFRL LTRDLKCVAS GDQCV
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Room Temperature
- Supplier:
- ReliaTech
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins