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Antibodies

CD80

Product Sizes
100 ug
£674.12
103-M144-100UG
About this Product
SKU:
103-M144
Additional Names:
Cd80; B71; Ly53; TSA1; Cd28l; Ly-53; MIC17
Application:
Flow Cytometry, Immunohistochemistry
Buffer:
PBS
translate.label.attr.clone:
MAB0713
Clonality:
Monoclonal
Extra Details:
B7-1 (CD80) and B7-2, together with their receptors CD28 and CTLA4, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. Although both CTLA4 and CD28 can bind to the same ligands, CTLA4 binds to B7-1 and B7-2 with a 20-100 fold higher affinity than CD28 and is involved in the downregulation of the immune response. B7-1 is expressed on activated B cells, activated T cells, and macrophages. B7-2 is constitutively expressed on interdigitating dendritic cells, Langerhans cells, peripheral blood dendritic cells, memory B cells, and germinal center B cells. Additionally, B7-2 is expressed at low levels on monocytes and can be upregulated through interferon gamma. B7-1 and B7-2 are both members of the Immunoglobulin superfamily.
Formulation:
lyophilized
Host:
Hamster
Immunogen:
Recombinant Mouse CD80 protein
Isotype:
IgG
Purification:
Protein G/A chromatography
Reactivities:
Mouse
Shipping Conditions:
Ambient
Storage Conditions:
-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
ReliaTech
Type:
Antibody: Monoclonal Antibody