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Antibodies

MIP-1 alpha

Product Sizes
100 ug
£365.88
102-P63-100UG
About this Product
SKU:
102-P63
Additional Names:
CCL3; MIP1A; SCYA3; G0S19-1; LD78ALPHA; MIP-1-alpha
Application:
ELISA, Western Blot
Buffer:
PBS
translate.label.attr.clone:
Rabbit IgG
Clonality:
Polyclonal
Extra Details:
Both MIP-1A Alpha and MIP-1B Beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1A Alpha and MIP-1B Beta exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1A Alpha selectively attracting CD8+ lymphocytes and MIP-1B Beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1A Alpha and MIP-1B Beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1A Alpha and MIP-1B Beta are active on human and murine hematopoietic cells. Recombinant human MIP-1A Alpha is a 7.8 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.
Formulation:
lyophilized from PBS
Host:
Rabbit
Immunogen:
Recombinant Human MIP-1 alpha
Purification:
Antigen-affinity purified
Reactivities:
Human
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C lyophilized. Aliquot. Avoid freeze/thaw cycles.
Supplier:
ReliaTech
Type:
Antibody: Polyclonal Antibody