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Antibodies

IL-12 receptor beta1

Product Sizes
100 ug
£674.12
101-M476-100UG
About this Product
SKU:
101-M476
Additional Names:
IL12RB1; CD212; IL12RB; IL-12R-BETA1
Application:
Flow Cytometry
Buffer:
PBS
translate.label.attr.clone:
7V24
Clonality:
Monoclonal
Extra Details:
The biological activities of IL-12 are mediated through a receptor complex composed of two class I cytokine receptor subunits designated IL-12 R beta 1 and IL-12 R beta 2. Both subunits are required for high-affinity binding and activity of IL-12. IL-12 R beta 1 binds specifically to IL-12 p40, a subunit of the heterodimeric IL-12, and is also a subunit of the IL-23 receptor complex, while IL-12 R beta 2 binds IL-12 p35. IL-12 Rs are predominantly expressed on NK cells and activated T (Th1) cells with some expression also on dendritic cells. Both IL-12 R subunit extracellular domains are composed of three fibronectin-like domains and two cytokine receptor homology domains. IL-12R beta 2 also has an extracellular Ig-like domain.
Formulation:
lyophilized
Host:
Mouse
Immunogen:
recombinant human IL-12R alpha 1 EC domain
Isotype:
IgG1
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
ReliaTech
Type:
Antibody: Monoclonal Antibody