CLEC9a
Product Sizes
100 ug
£674.12
101-M232-100UG
About this Product
- SKU:
- 101-M232
- Additional Names:
- C-type lectin domain family 9 member A, CD370
- Application:
- Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- 30L2
- Clonality:
- Monoclonal
- Extra Details:
- CLEC9A, a group V C-type lectin-like receptor, is located in the "Dectin-1 cluster" of related receptors, which are encoded within the natural killer (NK)-gene complex. Expression of human CLEC9A is highly restricted in peripheral blood, being detected only on BDCA3+ dendritic cells and on a small subset of CD14+CD16- monocytes. CLEC9A is expressed at the cell surface as a glycosylated dimer and can mediate endocytosis, but not phagocytosis. CLEC9A possesses a cytoplasmic immunoreceptor tyrosine-based activation-like motif that can recruit Syk kinase, and it was shown, using receptor chimeras, that this receptor can induce proinflammatory cytokine production.
- Formulation:
- lyophilized
- Host:
- Mouse
- Immunogen:
- Recombinant Human CLEC9a
- Isotype:
- IgG1
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- ReliaTech
- Type:
- Antibody: Monoclonal Antibody