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Antibodies

CLEC9a

Product Sizes
100 ug
£674.12
101-M232-100UG
About this Product
SKU:
101-M232
Additional Names:
C-type lectin domain family 9 member A, CD370
Application:
Flow Cytometry
Buffer:
PBS
translate.label.attr.clone:
30L2
Clonality:
Monoclonal
Extra Details:
CLEC9A, a group V C-type lectin-like receptor, is located in the "Dectin-1 cluster" of related receptors, which are encoded within the natural killer (NK)-gene complex. Expression of human CLEC9A is highly restricted in peripheral blood, being detected only on BDCA3+ dendritic cells and on a small subset of CD14+CD16- monocytes. CLEC9A is expressed at the cell surface as a glycosylated dimer and can mediate endocytosis, but not phagocytosis. CLEC9A possesses a cytoplasmic immunoreceptor tyrosine-based activation-like motif that can recruit Syk kinase, and it was shown, using receptor chimeras, that this receptor can induce proinflammatory cytokine production.
Formulation:
lyophilized
Host:
Mouse
Immunogen:
Recombinant Human CLEC9a
Isotype:
IgG1
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Ambient
Storage Conditions:
-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
ReliaTech
Type:
Antibody: Monoclonal Antibody