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Antibodies

MIP-1 alpha

Product Sizes
500 ug
£370.59
101-M14-500UG
About this Product
SKU:
101-M14
Additional Names:
CCL3; MIP1A; SCYA3; G0S19-1; LD78ALPHA; MIP-1-alpha
Application:
Block/Inhibit/Neutralise, ELISA
Buffer:
PBS
translate.label.attr.clone:
Rabbit IgG
Clonality:
Monoclonal
Extra Details:
Both MIP-1A Alpha and MIP-1B Beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1A Alpha and MIP-1B Beta exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1A Alpha selectively attracting CD8+ lymphocytes and MIP-1B Beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1A Alpha and MIP-1B Beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1A Alpha and MIP-1B Beta are active on human and murine hematopoietic cells. Recombinant human MIP-1A Alpha is a 7.8 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.
Formulation:
lyophilized from PBS
Host:
Mouse
Immunogen:
Recombinant Human MIP-1 alpha
Isotype:
IgG1, kappa
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C lyophilized. Aliquot. Avoid freeze/thaw cycles.
Supplier:
ReliaTech
Type:
Antibody: Monoclonal Antibody