anti-p16 Protein, DCS-50, mouse monoclonal antibody
Product Sizes
10 ug
£122.00
690074-10UG
50 ug
£255.00
690074-50UG
About this Product
- SKU:
- 690074
- Additional Names:
- Putative protein CDKN2A-DT, CDKN2A antisense RNA 1, CDKN2A antisense gene protein 1, Protein CDKN2A-AS1, Susceptibility protein NSG-x, CDKN2A-DT, C9orf53, CDKN2A-AS1
- Application:
- Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
- CE/IVD:
- RUO
- translate.label.attr.clone:
- DCS-50
- Clonality:
- Monoclonal
- Concentration:
- 100 ug/ml
- Extra Details:
- p16 (CDKN2A, p16Ink4A), is key regulator of the cell cycle and involved in cell cycle control and cellular senescence. It is a specific inhibitor for Cdk4 and Cdk6 and binds to the phosphorylated Cdk-cyclin complex. A disruption of this pathway is commonly observed in cancer. p16 is lost in the majority of tumor cell lines and in most primary tumors. It is not expressed in melanoma. In carcinoma driven by an HPV (human papilloma virus) infection, p16 is often overexpressed. The antibody is especially useful for immunoprecipitation. The epitope was localized within the 15 aa residues of the C-terminus of p16 protein.
- Formulation:
- PBS pH7.4 with 0.09% sodium azide and 0.5% BSA
- Host:
- Mouse
- Immunogen:
- Recombinant human p16 protein
- Isotype:
- IgG1
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Progen
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:690074