anti-Perilipin 1, PERI112, mouse monoclonal antibody, SN
Product Sizes
5 ml
£294.00
651156-5ML
About this Product
- SKU:
- 651156
- Additional Names:
- Perilipin-1, Lipid droplet-associated protein, PLIN1, PERI, PLIN
- Application:
- Immunocytochemistry, Immunofluorescence, Immunohistochemistry
- CE/IVD:
- RUO
- translate.label.attr.clone:
- PERI 112.17|PERI112
- Clonality:
- Monoclonal
- Extra Details:
- Perilipins build a family of phosphoproteins. The predominant forms in adipocytes, PLIN1 A and B arise by alternative RNA splicing from a single gene, generating polypeptides of 57 kDa and 46 kDa, respectively. The N-terminus, however, remains unchanged. The antibody reacts specifically with all PLIN1 variants located at the surface of intracellular storage lipid droplets present e.g. in the adrenal gland, sebaceous gland, adipocytes of white and brown adipose tissue and cultured cells such as 3T3-L1 adipocytes and cultured steroidogenic adrenal cortical and Leydig cells. It is also a useful pathological marker for steatogenesis e.g. in liver. It does not cross-react with adipophilin (ADRP, also named PLIN2) or TIP47 (also named PLIN3) proteins (or additional members of the PLIN/PAT-family, e.g. MLDP or OXPAT/PAT-1, also named PLIN5 or LSDP5). Tested reactivity on cultured cell lines: several human carcinoma cell lines; 3T3-L1 adipocytes.
- Formulation:
- Contains 0.09% sodium azide
- Host:
- Mouse
- Immunogen:
- Synthetic peptide of perilipin / PLIN1 (duplicated N-terminus of perilipin; aa 1-20)
- Isotype:
- IgG1
- Purification:
- Hybridoma cell culture supernatant
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Progen
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:651156