anti-Keratin Type II, AE3, mouse monoclonal antibody
Product Sizes
200 ug
£308.00
61806-200UG
About this Product
- SKU:
- 61806
- Application:
- Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
- CE/IVD:
- RUO
- translate.label.attr.clone:
- AE3
- Clonality:
- Monoclonal
- Concentration:
- 200 ug/ml
- Extra Details:
- AE 3 represents an excellent marker for distinguishing carcinoma from non-epithelial tumors. Tumors specifically detected: all epithelia and their neoplasms. Polypeptide reacting: Mr 53,000 to Mr 67,000 basic type II keratin polypeptides of human epithelial proteins (keratins - formerly also designated cytokeratins - nos. K1 - K8). Epitope has been mapped to aa 266-299 on alpha-helical rod domain (see Waseem et al., 2004). Reactivity on cultured cell lines: MCF-7, A-431, RT 112. Waseem A, Karsten U, Leigh IM, Purkis P, Waseem NH, Lane BE: Conformational changes in the rod domain of human keratin 8 following heterotypic association with keratin 18 and its implication for filament stability. Biochemistry 43, 1283-1295 (2004)
- Formulation:
- PBS pH 7.4 with 0.09% sodium azide
- Host:
- Mouse
- Immunogen:
- Human epidermal keratin
- Isotype:
- IgG1
- Purification:
- Affinity Purified
- Reactivities:
- Avian, Bovine, Human, Mouse, Non-human Primate, Rabbit, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Progen
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:61806