anti-Drebrin, MX823, mouse monoclonal antibody
Product Sizes
250 ul
£317.00
612128-250UL
About this Product
- SKU:
- 612128
- Additional Names:
- Drebrin, Developmentally-regulated brain protein, DBN1, D0S117E
- Application:
- Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
- CE/IVD:
- RUO
- translate.label.attr.clone:
- MX823
- Clonality:
- Monoclonal
- Extra Details:
- MX823 specifically reacts with drebrin, a widespread actin-associating protein of 70 kD (SDS-PAGE mobility shows Mr 120,000). It is enriched at junctional plaques, defining a specific microfilament anchorage system in polar epithelial cells. Positive staining was found in many tissues, including diverse epithelia and carcinoma (e.g. in epidermis basal cells are positive, whereas overlying cells are negative; also positive: regenerating epithelium during wound healing; basal cell carcinoma; skin melanoma), specific types of endothelia and smooth muscle; especially prominent in the mesangial cells of renal glomeruli and in the Sertoli cells of testis. Also positive: epithelia of hair follicles and eccrine sweat glands. Consistently negative were, however, hepatocytes and cross-striated muscle. Reactivity on cultured cell lines: primary human keratinocytes, U333, MCF-7, SV80, B16 (mouse melanoma cells).
- Formulation:
- Contains 0.09% sodium azide
- Host:
- Mouse
- Immunogen:
- Synthetic c-terminal peptide (aa632-649) coupled to KLH
- Isotype:
- IgG1
- Reactivities:
- Bovine, Canine, Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Progen
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:612128