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Antibodies

anti-Drebrin, MX823, mouse monoclonal antibody

Product Sizes
250 ul
£317.00
612128-250UL
About this Product
SKU:
612128
Additional Names:
Drebrin, Developmentally-regulated brain protein, DBN1, D0S117E
Application:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
CE/IVD:
RUO
translate.label.attr.clone:
MX823
Clonality:
Monoclonal
Extra Details:
MX823 specifically reacts with drebrin, a widespread actin-associating protein of 70 kD (SDS-PAGE mobility shows Mr 120,000). It is enriched at junctional plaques, defining a specific microfilament anchorage system in polar epithelial cells. Positive staining was found in many tissues, including diverse epithelia and carcinoma (e.g. in epidermis basal cells are positive, whereas overlying cells are negative; also positive: regenerating epithelium during wound healing; basal cell carcinoma; skin melanoma), specific types of endothelia and smooth muscle; especially prominent in the mesangial cells of renal glomeruli and in the Sertoli cells of testis. Also positive: epithelia of hair follicles and eccrine sweat glands. Consistently negative were, however, hepatocytes and cross-striated muscle. Reactivity on cultured cell lines: primary human keratinocytes, U333, MCF-7, SV80, B16 (mouse melanoma cells).
Formulation:
Contains 0.09% sodium azide
Host:
Mouse
Immunogen:
Synthetic c-terminal peptide (aa632-649) coupled to KLH
Isotype:
IgG1
Reactivities:
Bovine, Canine, Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
Please refer to datasheet
Supplier:
Progen
Type:
Antibody: Monoclonal Antibody
  • Manufacturer's Data Sheet:612128