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Antibodies

anti-p16 Protein, DCS-50, mouse monoclonal antibody

Product Sizes
50 ug
£255.00
61074-50UG
About this Product
SKU:
61074
Additional Names:
Putative protein CDKN2A-DT, CDKN2A antisense RNA 1, CDKN2A antisense gene protein 1, Protein CDKN2A-AS1, Susceptibility protein NSG-x, CDKN2A-DT, C9orf53, CDKN2A-AS1
Application:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
CE/IVD:
RUO
translate.label.attr.clone:
DCS-50
Clonality:
Monoclonal
Concentration:
50 ug/ml
Extra Details:
p16 (CDKN2A, p16Ink4A), is key regulator of the cell cycle and involved in cell cycle control and cellular senescence. It is a specific inhibitor for Cdk4 and Cdk6 and binds to the phosphorylated Cdk-cyclin complex. A disruption of this pathway is commonly observed in cancer. p16 is lost in the majority of tumor cell lines and in most primary tumors. It is not expressed in melanoma. In carcinoma driven by an HPV (human papilloma virus) infection, p16 is often overexpressed. The antibody is especially useful for immunoprecipitation. The epitope was localized within the 15 aa residues of the C-terminus of p16 protein.
Formulation:
Lyophilized; reconstitute in 1 ml dist. water (final solution contains 0.09% sodium azide, 0.5% BSA in PBS buffer, pH 7.4)
Host:
Mouse
Immunogen:
Recombinant human p16 protein
Isotype:
IgG1
Physical State:
Lyophilized
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C reconstituted. Aliquot. Avoid freeze/thaw cycles.
Supplier:
Progen
Type:
Antibody: Monoclonal Antibody
  • Manufacturer's Data Sheet:61074