anti-LRP, 5A6, mouse monoclonal antibody
Product Sizes
50 ug
£315.00
61066-50UG
About this Product
- SKU:
- 61066
- Application:
- Immunohistochemistry, Western Blot
- CE/IVD:
- RUO
- translate.label.attr.clone:
- 5A6
- Clonality:
- Monoclonal
- Concentration:
- 50 ug/ml
- Extra Details:
- 5A6 specifically reacts with the 85 kDa b-chain of human LRP/a2MR which is expressed in a restricted spectrum of cell types (for a recent review cf. Herz & Strickland). A strong immunohistochemical reaction is seen in hepatocytes, tissue macrophages, subsets of neurones and astrocytes in the central nervous system, fibroblasts, smooth muscle cells, and monocyte-derived foam cells in atherosclerotic lesions in the arterial wall. The antibody can also be used for the characterization of a subset of myelo-monocytic subtypes of chronic and acute leukemia (CD 91). Neutralizing effects of 5A6 have also been reported (Basu et al., 2001). Basu S, Binder RJ, Ramalingam T, Srivastave PK: CD91 is a common receptor for heat shock proteins gp96, hsp90, hsp 70, and calreticulin. Immunity 14, 303-313 (2001)
- Formulation:
- Lyophilized; reconstitute in 1 ml dist. water (final solution contains 0.5% BSA in PBS buffer, pH 7.4)
- Host:
- Mouse
- Immunogen:
- Human LRP/alpha2MR
- Isotype:
- IgG2b
- Physical State:
- Lyophilized
- Purification:
- Affinity Purified
- Reactivities:
- Hamster, Human, Mouse, Rabbit, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C reconstituted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Progen
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:61066