anti-Calprotectin-S100A9+A8/A9, 23-3-4, mouse monoclonal antibody
Product Sizes
100 ug
£354.00
610188-100UG
About this Product
- SKU:
- 610188
- Application:
- ELISA, Immunohistochemistry, Western Blot
- CE/IVD:
- RUO
- translate.label.attr.clone:
- 23-3-4
- Clonality:
- Monoclonal
- Concentration:
- 100 ug/ml
- Extra Details:
- Calprotectin is a functional heterocomplex of small EF hand calcium binding proteins S100A8 and S100A9. The heterocomplex is expressed in various cell types and tissues and induced upon inflammation. The complex is released by neutrophilic granulocytes in inflammatory disorders such as inflammatory bowel disease and rheumatoid arthritis. Released Calprotectin serves as a leukocyte chemoattractant and modulates inflammation via damage receptors. Via its binding to the receptor of advanced glycation end-products (RAGE), calprotectin is implicated in chronic inflammation and cancer formation. Tissue expression: strong expression in myeloid cells and psoriatic keratinocytes. The antibody recognizes both the S100A8/A9 heterocomplex as well as S100A9 alone but not S100A8.
- Formulation:
- Lyophilized; reconstitute in 1 ml dist. water (final solution contains 0.09% sodium azide, 0.5% BSA in PBS buffer, pH 7.4)
- Host:
- Mouse
- Immunogen:
- Recombinant protein
- Isotype:
- IgG2b
- Physical State:
- Lyophilized
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C reconstituted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Progen
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:610188
