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Antibodies

anti-Calprotectin-S100A9+A8/A9, 23-3-4, mouse monoclonal antibody

Product Sizes
100 ug
£354.00
610188-100UG
About this Product
SKU:
610188
Application:
ELISA, Immunohistochemistry, Western Blot
CE/IVD:
RUO
translate.label.attr.clone:
23-3-4
Clonality:
Monoclonal
Concentration:
100 ug/ml
Extra Details:
Calprotectin is a functional heterocomplex of small EF hand calcium binding proteins S100A8 and S100A9. The heterocomplex is expressed in various cell types and tissues and induced upon inflammation. The complex is released by neutrophilic granulocytes in inflammatory disorders such as inflammatory bowel disease and rheumatoid arthritis. Released Calprotectin serves as a leukocyte chemoattractant and modulates inflammation via damage receptors. Via its binding to the receptor of advanced glycation end-products (RAGE), calprotectin is implicated in chronic inflammation and cancer formation. Tissue expression: strong expression in myeloid cells and psoriatic keratinocytes. The antibody recognizes both the S100A8/A9 heterocomplex as well as S100A9 alone but not S100A8.
Formulation:
Lyophilized; reconstitute in 1 ml dist. water (final solution contains 0.09% sodium azide, 0.5% BSA in PBS buffer, pH 7.4)
Host:
Mouse
Immunogen:
Recombinant protein
Isotype:
IgG2b
Physical State:
Lyophilized
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C reconstituted. Aliquot. Avoid freeze/thaw cycles.
Supplier:
Progen
Type:
Antibody: Monoclonal Antibody
  • Manufacturer's Data Sheet:610188