anti-Perilipin 2, AP125, mouse monoclonal antibody
Product Sizes
50 ug
£377.00
610102-50UG
About this Product
- SKU:
- 610102
- Additional Names:
- PLIN2, ADRP
- Application:
- Immunohistochemistry, Western Blot
- CE/IVD:
- RUO
- translate.label.attr.clone:
- AP125
- Clonality:
- Monoclonal
- Concentration:
- 50 ug/ml
- Extra Details:
- Perilipin 2/Adipophilin/ADRP/PLIN2 is a ubiquitous component of lipid droplets. It has been found in milk fat globule membranes and on the surface of lipid droplets in various cultured cell lines; inducible by etomoxir. Enhanced expression of Perilipin 2/Adipophilin/ADRP/PLIN2 is a useful marker for pathologies characterized by increased lipid droplet accumulation. Such diseases include atheroma, steatosis, obesity and certain cases of liposarcoma. It also seems to be a potent marker for atherosclerosis. ADRP can also be used to study virus entry via lipid droplets. Polypeptide reacting: Perilipin 2/Adipophilin/ADRP/PLIN2, MW 48,100 (calculated from aa sequence data); apparent Mr 52,000 (after SDS-PAGE); pI 6.72. Immunolocalization: Perilipin 2/Adipophilin/ADRP/PLIN2 is positively detected in the glandular cells of lactating mammary gland (ductal cells are negative), zona fasciculata of the adrenal gland, Sertoli cells of the testis, and in fat-accumulating hepatocytes of alcoholic cirrhotic fatty liver; adipocytes are negative.Also positively stained are lipid-storing CD 68-positive macrophages. Tested cultured cell lines: PLC, MDCK. Learn more about PROGEN Perilipin antibodies.
- Formulation:
- Lyophilized; reconstitute in 1 ml dist. water (final solution contains 0.09% sodium azide, 0.5% BSA in PBS buffer, pH 7.4)
- Host:
- Mouse
- Immunogen:
- Synthetic peptide (aa 5-27 from N-terminus of human adipophilin/PLIN2)
- Isotype:
- IgG1
- Physical State:
- Lyophilized
- Purification:
- Affinity Purified
- Reactivities:
- Bovine, Canine, Human, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C reconstituted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Progen
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:610102
