anti-Cadherin 6, 2B6, mouse monoclonal antibody
Product Sizes
1 ml
£330.00
16111-1ML
About this Product
- SKU:
- 16111
- Additional Names:
- Cadherin-6, Kidney cadherin, K-cadherin, CDH6
- Application:
- Immunohistochemistry
- CE/IVD:
- RUO
- translate.label.attr.clone:
- 2B6
- Clonality:
- Monoclonal
- Extra Details:
- The cadherin gene family encodes calcium-dependent adhesion molecules that promote homophilic interactions among cells. All cadherins are single-pass transmembrane proteins with a variable number of extracellular domains (EC; 110 amino acids long). Classical cadherins consist of five EC domains and a conserved cytoplasmic domain and are divided in type I and type II subgroups. Type I comprises cadherin E, N, P, and R. Type II include cadherin-5, -6, -8, -11, and -12. During embryogenesis differential expression of cadherins can drive morphogenesis by stimulating cell aggregation, defining boundaries between groups of cells and promoting cell migration. Cadherin-6 seems to be required for the early aggregation of induced mesenchymal cells and their subsequent conversion to epithelium. Positive control: Embryonic kidney (e.g. establishment of developmental pattern of nephrons)
- Formulation:
- Contains 0.09% sodium azide
- Host:
- Mouse
- Immunogen:
- GST fusion protein of part of the extracellular domain of cadherin 6 (K-Cadherin)
- Isotype:
- IgG1
- Purification:
- Hybridoma cell culture supernatant
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Progen
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:16111
