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Antibodies

anti-CD44, DF1485, mouse monoclonal antibody

Product Sizes
1 ml
£251.00
16080-1ML
About this Product
SKU:
16080
Application:
Immunohistochemistry, Western Blot
CE/IVD:
RUO
translate.label.attr.clone:
DF1485
Clonality:
Monoclonal
Extra Details:
CD44 (HCAM) is a transmembrane protein expressed by lymphocytes, erythrocytes and several normal epithelial cells and is a member of the CAM family. It is involved in lymphocyte homing, T-lymphocyte activation, interaction with hyaluronic acid and may act as an adhesion molecule. The human CD44 is composed of 19 exons, 9 variably expressed due to alternative splicing of mRNA; standard CD44 (CD44s) is composed of exons 1-5 and 15-19. The loss of CD44s expression predicts unfavorable outcome in bladder cancers, squamous cell carcinomas of the skin, prostatic adenocarcinoma and neuroblastomas. In immunoblotting the antibody reacts with a glycoprotein isolated from hematopoetic cells and epithelial cells with a respective molecular weight of 29-37 kD and 51 kD. Positive control: Tonsil (cell membrane staining).
Formulation:
Contains 0.09% sodium azide
Host:
Mouse
Immunogen:
CD44 antigen (PGp-1) purified from lymphocyte membrane
Isotype:
IgG1
Purification:
Hybridoma cell culture supernatant
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Please refer to datasheet
Supplier:
Progen
Type:
Antibody: Monoclonal Antibody
  • Manufacturer's Data Sheet:16080