Skip to content

Basket

You currently have no items in your basket.

Total (excl. vat) £0.00
View basket & checkout
Proteins and Peptides

Z-Phe-Arg-AFC (Cathepsin L Substrate)

Product Sizes
10 mg
ECH-866-75-10MG
About this Product
SKU:
ECH-866-75
Extra Details:
CAS Number: 65147-22-0Molecular Weight: 666.24Salt Form: TFAPurity: >96%Sequence (3-letter): Z-Phe-Arg-AFCSequence (1-letter): Z-FR-AFCStorage: -20 °C or belowZ-Phe-Arg-AFC is a fluorogenic for Cathepsin L. Cathepsin L is a lysosomal cysteine protease with an important role in initiating protein degradation. Cathepsin L is also upregulated in several cancers and has been suggested as a drug target. In addition extracellular secretion of Cathepsin L by tumors implicates it as a potential serum biomarker for cancer progression.Activity is quantified by release of free fluorescent 7-amino-4-trifluoromethylcoumarin (AFC) which excites at 395-400 nm and emits at 495-505 nm.
Molecular Weight:
666.24
Sequence:
Z-Phe-Arg-AFC
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
Echelon Biosciences
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides