ACRO Biosystems
ACROBiosystems is a leading manufacturer of recombinant proteins and other critical reagents to support the development of target therapeutics, vaccines, and diagnostics. The company employs an application-oriented development strategy, with a particular focus on product design, quality control and solution-based support. Their products and services enable anyone in the field of drug development to have a more intuitive and streamlined process.
View all ACRO Biosystems Products
Seamless Transition to GMP Products
The smooth transition from premium-grade components to GMP products negates the necessity for extra comparability studies. This results in a seamless progression of cell therapy products from premium grade to GMP during the transition into clinical trials.
ACRO Biosystems is known for its commitment to providing Good Manufacturing Practice (GMP)-compliant products, understanding the importance of raw and ancillary materials. The company offers a range of GMP-grade recombinant proteins and antibodies that adhere to regulatory standards, ensuring the integrity and safety of these critical reagents for use in clinical research, drug development, and manufacturing processes. ACRO Biosystems' GMP products are designed to meet the rigorous quality control measures necessary for applications in the production of biologics and therapeutic proteins.
GMP-certified cytokines from ACRO Biosystems ensures adherence to Good Manufacturing Practice standards, aligning with regulatory recommendations for immune cell therapy. These high-quality cytokines, including IL-15, IL-7, and IL-21, play a crucial role as key raw materials in the activation and amplification of T/NK cells. This commitment to GMP-grade materials enhances the safety, effectiveness, and compliance of immune cell therapy products, contributing to their successful development and application in the research and treatment of various malignant tumours.
Full Length Active Gallery (FLAG)
Dysregulation of transmembrane proteins is associated with numerous human diseases, making them desirable targets for drug development and ACRO’s Full Length Active Gallery (FLAG) provides a range of comprehensive solutions to empower researchers. The transmembrane region directly interacts with the phospholipid bilayer, forming a vital channel for the transport of ions and molecules, as well as facilitating the relay of activation and response reactions to external stimuli. These reactions initiate downstream signal pathways, influencing cell metabolism, activity, and regulation.
ACRO presents 3 different technology platforms available for researchers to investigate transmembrane proteins. These include a VLP (Virus Like Particle) platform, a nanodisc platform and a detergent micelle platform, each of which with their unique advantages.
VLP Platform | Detergent Micelle Platform | Nanodisc Platform |
The membrane protein-VLP complex presents correctly folded multi-pass TPs on the cell membrane, facilitating the induction and screening of functional antibodies that recognise the natural conformation of the target | A comprehensive platform for expressing, purifying, and stabilising challenging drug target TPs in both insect and mammalian cells. ACRO Biosystems conducts detergent screening, such as DDM/CHS to enhance solubility and preserve the native fold of these proteins in vitro. | ACRO’s consisting of membrane scaffold proteins (MSPs) and phospholipid molecules. Transmembrane proteins (TPs) can be incorporated into the unique Nanodisc structure after detergent removal, preserving their native folding, biological activity, and enhancing hydrophilicity. This detergent-free Nanodisc formulation is also compatible in CAR expression tests. |
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Antibodies and Proteins
ACRO Biosystems is recognised for its expertise in producing high-quality antibodies and proteins crucial for advancing biomedical research and drug development. ACRO's antibodies are typically developed through recombinant technology, ensuring specificity and reliability in various applications, such as immunohistochemistry, Western blotting, and enzyme-linked immunosorbent assays (ELISAs).
The company's diverse portfolio of recombinant proteins spans cytokines, growth factors, and other key signalling molecules, providing researchers with essential tools for investigating cellular processes and disease mechanisms. Known for their commitment to quality, ACRO Biosystems plays a vital role in supporting the scientific community by delivering reliable reagents that contribute to advancements in therapeutic discovery and diagnostic technologies.
Cell and Gene Therapy
ACRO Biosystems has been actively involved in the field of cell and gene therapy by offering a comprehensive range of products tailored to support cutting-edge research and development. The company provides a variety of key reagents essential for cell and gene therapy applications, including recombinant proteins, CAR Targets, and assay kits designed to facilitate the study of crucial cellular processes, identify therapeutic targets, and assess the efficacy of novel treatments. ACRO Biosystems' commitment to quality and innovation positions them as a valuable partner for researchers and pharmaceutical developers working on advancing cell and gene therapies.
ACRO’s Product Ranges | |||
Proteins | |||
Antibodies | |||
Assay Kits | |||
Nuclease | |||
Cytokine Targets | |||
GMP Grade | |||
GMP Grade Cytokines | |||
Matrigengel Matrix |
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Features: ClinMax Cytokine Detection Kit
- Quick & Easy-to-use:
2 hour assay with only 7 steps required.
- Consistent:
Calibrated using NIBSC/WHO standards to ensure batch-to-batch consistency.
- Strict Quality Control:
High sensitivity, specificity, accuracy, linearity and inter/intra precision.
- Minimal Matrix Interference:
Low matrix interference verified in cell culture supernatant and serum.
CD73 Products from ACROBiosystems
A novel target for immunotherapy. a specific immunotherapeutic target to improve antitumor immune responses to immune checkpoint therapy in glioblastoma multiforme.
Bring pre-labelled biotinylated proteins directly to your bench from ACROBiosystems!