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Antibodies

Alpha Synuclein Antibody: HRP

Product Size(s)
100 ug
£494.00
SPC-800D-HRP
Academic Pricing
Please contact us for academic pricing.
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About this Product
SKU:
SPC-800D-HRP
Additional Names:
Alpha Synuclein Antibody, Non-A4 component of amyloid precursor Antibody, MGC105443 Antibody, OTTHUMP00000218552 Antibody, MGC110988 Antibody, OTTHUMP00000218553 Antibody, Synuclein alpha 140 Antibody, alphaSYN Antibody, Parkinson disease familial 1 Antibody, OTTHUMP00000218554 Antibody, Parkinson disease (autosomal dominant, Lewy body) 4 Antibody, Synuclein, alpha (non A4 component of amyloid precursor) Antibody, OTTHUMP00000218549 Antibody, Non A4 component of amyloid precursor Antibody, MGC127560 Antibody, SYN Antibody, SNCA Antibody, MGC64356 Antibody, Non A4 component of amyloid Antibody, PARK4 Antibody, Alpha synuclein Antibody, PARK 1 Antibody, Snca synuclein, Synuclein alpha Antibody, Non-A4 component of amyloid, precursor of Antibody, OTTHUMP00000218551 Antibody, PARK 4 Antibody, PARK1 Antibody, Alpha-synuclein, isoform NACP140 Antibody, Non-A-beta component of alzheimers disease amyloid, Non-A beta component of AD amyloid Antibody, NACP Antibody, SYUA_HUMAN Antibody, Alpha-synuclein Antibody, Non A beta component of AD amyloid Antibody
Application:
ELISA, Immunohistochemistry, Western Blot
CE/IVD:
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Clonality:
Polyclonal
Conjugate:
HRP
Concentration:
1 mg/ml
Extra Details:
Alpha-Synuclein (SNCA) is expressed predominantly in the brain, where it is concentrated in presynaptic nerve terminals (1). Alpha-synuclein is highly expressed in the mitochondria of the olfactory bulb, hippocampus, striatum and thalamus (2). Functionally, it has been shown to significantly interact with tubulin (3), and may serve as a potential microtubule-associated protein. It has also been found to be essential for normal development of the cognitive functions; inactivation may lead to impaired spatial learning and working memory (4). SNCA fibrillar aggregates represent the major non A-beta component of Alzheimers disease amyloid plaque, and a major component of Lewy body inclusions, and Parkinson's disease. Parkinson's disease (PD) is a common neurodegenerative disorder characterized by the progressive accumulation in selected neurons of protein inclusions containing alpha-synuclein and ubiquitin (5, 6).
Gene Details:
SNCA
Host:
Rabbit
Immunogen:
Recombinant Human alpha Synuclein Fibril
Protein Details:
P37840
Purification:
Protein A Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C
Supplier:
StressMarq Biosciences
Type:
Antibody: Polyclonal Antibody
Size:
100 ug
Preservative:
0.09% Sodium azide
Accession:
NP_000336.1